The Effect of Vitamin-Mineral Supplementation on the Effects of Juvenile Delinquency

There is disagreement among professionals involved in research and treatment of ADHD as to the usefulness of vitamin and mineral supplementation as an effective treatment strategy. In a recently published review of the literature on alternative treatments it was concluded that mineral supplementation (e.g. iron, magnesium) in ADHD children shown to be deficient in those minerals yielded promising results in several studies and warranted additional research using double-blind, placebo-controlled trials. However, no convincing data on the use of vitamin supplementation has been reported that I am aware of, and a recent review of alternative treatments for ADHD is very negative about this approach. It should be noted that this applies to mega-vitamin treatments in which children are given very large doses of certain vitamins, rather than simply bringing children up to currently recommended levels.

 

You may be curious about the impact of possible vitamin and mineral deficiencies on aggression and other forms of antisocial behavior. Although such behavior is not among the core symptoms of ADHD, and many children with ADHD do not display any significant antisocial characteristics, it is widely documented that such behaviors do occur at elevated rates among ADHD children. Might vitamin and mineral deficiencies stemming from poor nutritional habits play a role in the development of antisocial behavior among school-age children?

 

This question was addressed in a study published in the Journal of Alternative and Complementary Medicine (Schoenthaler, S.J., & Bier, I.D., Vol. 6, 2000.) Participants in this study included 468 children between the ages of 6 and 12 from two predominantly Hispanic elementary schools. This represented approximately 75% of the total population of those schools from which parental consent to participate was obtained.

 

The design of this study was simple and straightforward. Children were randomly assigned to either an experimental group or a control group. Care was taken to ensure that the groups were equated in terms of children’s intellectual ability. Children in the experimental group received two chewable tablets each day for four months that provided daily vitamin-mineral supplementation at 50% of the U.S. recommended daily allowance. The supplement was designed to raise vitamin-mineral intake up to the levels currently recommended by the National Academy of Sciences, which is quite different from some popular mega-vitamin approaches. Children in the control group received two identical looking placebo tablets (these

tablets provided no vitamin or mineral supplementation).

 

Throughout this time period, the antisocial behavior of study participants at school was carefully tracked. Children were disciplined for antisocial behavior including things like fighting, threatening others, property destruction, and refusing to complete their work. The numbers of such behaviors that occurred over the 4-month study period and were deemed by school staff to reflect serious rule violations were tallied. This enabled the researchers to compare the rates of antisocial acts among those children receiving the vitamin-mineral supplementation treatment with those children receiving only a placebo.

 

Rather than make this comparison among all the children participating, the authors restricted their analysis to 80 children (40 in each group) who had been formally disciplined for violating school rules during the 4 months prior to the start of the study.  This was done because they were interested in whether vitamin-mineral supplementation resulted in reduced antisocial behavior; and among those children who had not committed any prior antisocial acts according to school records, no such improvement would be possible. It is important to note that the children in the supplement and placebo groups did not differ on any pretreatment measures examined (such as IQ or their number of prior offenses).

 

RESULTS

 

Before examining the impact of the vitamin-mineral supplementation on children’s rates of serious rules violations, the authors first examined whether children could detect whether they had received the supplement or the placebo. The majority of children--regardless of actual group assignment--guessed that they had received the supplements, and the rate of accurate guessing did not differ between the groups.

 

During the 4-month intervention period, the children who received the active vitamin-mineral supplementation had an average rate of serious rule violations at school of 1 per child. For children receiving the placebo, the average number of serious rules violations nearly doubled to 1.875 per child. This is a statistically significant difference. The reason for the higher average rate among the placebo group was due almost entirely to a relatively small number of children who committed multiple offenses. Thus, among children receiving the supplements, there was only a single child who committed more than one offense during the 4-month study period. Among the placebo group, in contrast, there were 9 students who committed multiple offenses.

 

SUMMARY AND IMPLICATIONS

 

This well designed study provides solid preliminary evidence that for some children, vitamin and mineral deficiencies may play a significant role in their behavioral difficulties. The authors suggest that this occurs because of the adverse affect that vitamin and mineral deficiencies can have on brain functioning. They also note that their findings replicate those that have been reported in several prior studies.

 

This cannot be concluded with certainty for several reasons, however. First, we do not know whether those children in the placebo group who committed multiple offenses were actually deficient in key vitamin or minerals to begin with because such an assessment was not conducted. Second, we do not know whether providing active supplements to the more serious offenders in the placebo group would have resulted in a reduction in their antisocial behavior. Such a finding would have been particularly compelling, although this was probably not possible to do because it would have extended the study beyond the school year.

 

It is also important to emphasize that because children in this study were not selected according to core ADHD symptoms, and ADHD symptoms were not one of the outcome measures reported, the implications of these results for children with ADHD are unclear.  Thus, this particular study provides no

information on whether vitamin and mineral deficiencies are related to ADHD symptoms and whether supplementation might be helpful with these symptoms. One could interpret these results as suggesting that vitamin and mineral supplementation may be helpful in minimizing the amount of antisocial behavior engaged in by children with ADHD, although the caveats noted above would certainly apply and a careful replication of this work is necessary.


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